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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM L-540 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM L-540 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM L-540 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM L-540 Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.10 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.20 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.50 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 1.00 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 5.00 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 10.00 µM Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM PAKHZT (xenograft) p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM PAKRSL (xenograft) p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM PALNTB (xenograft) p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM PAKYEP (xenograft) p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM PALJDL (xenograft) p-STAT1
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) p-STAT1
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) p-STAT1