| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
HD-LM2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
HD-LM2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
HD-LM2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
HD-LM2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
L-428 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
L-428 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
L-428 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
L-428 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
KM-H2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
KM-H2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
KM-H2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
KM-H2 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
L-540 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
L-540 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
L-540 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
L-540 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Flow cytometry |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
NCI-H1650 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
HCC 827 |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
AGS |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.30 µM |
Hep3B |
Homo sapiens |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
786-O |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
786-O |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Renca |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Renca |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
KCNR |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
KCNR |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
KCNR |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
KCNR |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Rh18 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Rh18 |
Homo sapiens |
|
STAT3 |
|
