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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 5.00 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 5.00 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 5.00 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 5.00 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Real Time PCR 0.50 µM TC32 Homo sapiens
AZD1480 Influence on tumor growth Tumer volume 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Tumer volume 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Tumer volume 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice