| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
25.00 mg/kg |
NEU |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
50.00 mg/kg |
NEU |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
25.00 mg/kg |
LYM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
50.00 mg/kg |
LYM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
25.00 mg/kg |
MONO |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on hematologic parameters |
HEMAVET |
50.00 mg/kg |
MONO |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity |
Immunization |
25.00 mg/kg |
|
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT4 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT1 |
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on the Priming and Expansion Phases of EAE |
Immunization |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
RD |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh41 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh30 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
BT-12 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
TC-71 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-9 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-258 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
SJ-GBM2 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
HB-1643 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
NB-EBc1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-90 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-136 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
NALM-6 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
COG-LL-317 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
RS4;11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
MOLt-4 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CCRF-CEM GM |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CCRF-CEM-SY |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Kasumi-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Karpas-299 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Ramos-RA1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-6 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-13 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-13 |
Homo sapiens |
|
|
|
