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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein-protein interaction Immunoprecipitation 400.00 nM PC-3 Homo sapiens STAT5
AZD1480 Influence on protein-protein interaction Immunoprecipitation 200.00 nM PC-3 Homo sapiens STAT5
AZD1480 Influence on protein-protein interaction Immunoprecipitation 100.00 nM PC-3 Homo sapiens STAT5
AZD1480 Influence on protein-protein interaction Immunoprecipitation 50.00 nM PC-3 Homo sapiens STAT5
AZD1480 Influence on protein-protein interaction Immunoprecipitation 25.00 nM PC-3 Homo sapiens STAT5
AZD1480 Influence on protein translocation Immunostaining 50.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein translocation Immunostaining 100.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein translocation Immunostaining 200.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein translocation Immunostaining 50.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein translocation Immunostaining 100.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein translocation Immunostaining 200.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 25.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 50.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 100.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 250.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 500.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 1000.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on protein-DNA interaction EMSA 25.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 50.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 100.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 250.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 500.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on protein-DNA interaction EMSA 1000.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 3.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 10.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 30.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 100.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 300.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 1000.00 nM PC-3 Homo sapiens STAT5A
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 3.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 10.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 30.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 100.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 300.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on transcriptional activity of protein Luciferase Reporter Gene Assay 1000.00 nM PC-3 Homo sapiens STAT5B
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM CWR22Rv1 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM PC-3 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM DU145 Homo sapiens
AZD1480 Influence on cell apoptosis FACS 0.50 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis FACS 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis FACS 1.50 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis Fluorometric immunosorbent enzyme assay 800.00 nM CWR22Rv1 Homo sapiens
AZD1480 Influence on cell apoptosis Fluorometric immunosorbent enzyme assay 800.00 nM CWR22Pc Homo sapiens
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 10.00 mg/kg CWR22Rv1 Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 30.00 mg/kg CWR22Rv1 Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 10.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Rv1 Mus musculus STAT5A
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Rv1 Mus musculus STAT5B