| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
400.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
200.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
25.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
200.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
200.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
25.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
250.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
500.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
25.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
250.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
500.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
10.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
30.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
300.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
10.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
30.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
300.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
PC-3 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
0.50 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
1.00 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
1.50 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Fluorometric immunosorbent enzyme assay |
800.00 nM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Fluorometric immunosorbent enzyme assay |
800.00 nM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
10.00 mg/kg |
CWR22Rv1 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
30.00 mg/kg |
CWR22Rv1 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
10.00 mg/kg |
CWR22Pc |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
30.00 mg/kg |
CWR22Pc |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
30.00 mg/kg |
CWR22Rv1 |
Mus musculus |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
30.00 mg/kg |
CWR22Rv1 |
Mus musculus |
|
STAT5B |
|
