| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
800.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
400.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
200.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein-protein interaction |
Immunoprecipitation |
25.00 nM |
PC-3 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
10.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
20.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
30.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
60.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
100.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
200.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
15.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
30.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
60.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
100.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
200.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
300.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
400.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
10.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
20.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
30.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
60.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
100.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
200.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
400.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
10.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
20.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
30.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
60.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
100.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
200.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
400.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein translocation |
Immunostaining |
200.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
25.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
50.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
250.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
500.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
10.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
