| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
DU145 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
DU145 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDA-MB-468 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDA-MB-468 (xenograft) |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDA-MB-468 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation |
SRB assay |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
SRB assay |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
SRB assay |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
SRB assay |
1.00 µM |
PCCI3 |
Rattus norvegicus |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometry |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometry |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometry |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
TUNEL |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
TUNEL |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
TUNEL |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
STAT3 |
|
