| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein translocation in presence of OSM |
Immunofluorescence |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein translocation in presence of OSM |
Immunofluorescence |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein translocation in presence of OSM |
Immunofluorescence |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
50.00 mg/kg |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
LN-17 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
LN-17 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
0.10 µM |
LN-17 |
Homo sapiens |
|
STAT3:STAT3 |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
0.50 µM |
LN-17 |
Homo sapiens |
|
STAT3:STAT3 |
|
| AZD1480 |
Influence on protein-DNA interaction |
EMSA |
1.00 µM |
LN-17 |
Homo sapiens |
|
STAT3:STAT3 |
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometry- annexin V staining |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometry- annexin V staining |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometry- annexin V staining |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
