| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
HD-LM2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
HD-LM2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
HD-LM2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
HD-LM2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
L-428 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
L-428 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
L-428 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
L-428 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
KM-H2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
KM-H2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
KM-H2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
KM-H2 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
L-540 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
L-540 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
L-540 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
L-540 |
Homo sapiens |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
STAT5 |
|
