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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM KM-H2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM KM-H2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM KM-H2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM KM-H2 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM L-540 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM L-540 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM L-540 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM L-540 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM NCI-H1650 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM HCC 827 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM AGS Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM Hep3B Homo sapiens STAT3