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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Influence on protein activity Western Blot 0.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.01 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.03 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.10 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 1.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 3.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Influence on protein activity Western Blot 0.30 µM NCI-H1650 Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM NCI-H1650 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM HCC 827 Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM HCC 827 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM AGS Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM AGS Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM Hep3B Homo sapiens p-STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM Hep3B Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM MEF-Stat3-YFP Mus musculus p-STAT3 (Y705)