| AZD1480 |
Influence on cell proliferation |
Trypan blue exclusion assay |
3.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
Trypan blue exclusion assay |
4.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
Trypan blue exclusion assay |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 1 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 1 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 1 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 2 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 2 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 2 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 3 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 3 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 3 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
OCL-LY7 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
OCL-LY7 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
5.00 µM |
OCL-LY7 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on gene expression |
Real Time PCR |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on gene expression |
Real Time PCR |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Flow cytometry |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
2.00 µM |
MDCK |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
5.00 µM |
MDCK |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell cycle |
Ki67/DAPI cell proliferation assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.01 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.03 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.30 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
p-STAT5 |
|
