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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-540 Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM 4C8 Homo sapiens
AZD1480 Inhibition of protein signalling in human glioblastoma xenograft tumors RT-qPCR 1.00 µM Xenograft X1016 Mus musculus athymic nude mice