| AZD1480 |
Influence on gene expression |
Real Time PCR |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.25 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.25 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.20 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
10.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Immunoprecipitation |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Immunoprecipitation |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
|
|
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
10.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
10.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
10.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
10.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
|
|
