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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Inhibition of in vitro xenograft growth Western Blot 30.00 mg/kg Xenograft X1046 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM BMDM Mus musculus c57BL/6
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM BMDM Mus musculus c57BL/6
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.00 µM BMDM Mus musculus c57BL/6
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 4.00 µM BMDM Mus musculus c57BL/6