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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM L-540 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM L-540 Homo sapiens
AZD1480 Influence on gene expression Real Time PCR 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice