| AZD1480 |
Influence on cytokine secretion |
ELISA |
1.00 µM |
HD-LM2 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cytokine secretion |
ELISA |
1.00 µM |
L-428 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cytokine secretion |
ELISA |
1.00 µM |
L-540 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Inhibition of protein signalling in human glioblastoma xenograft tumors |
RT-qPCR |
1.00 µM |
Xenograft X1016 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Inhibition of in vitro xenograft growth |
Quantitative RT-PCR |
30.00 mg/kg |
Xenograft X1046 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
