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Experiments
| Compound | Investigated event | Experiment type | Concentration | Cell line | Organism | Animal model | Stat protein | Details |
|---|---|---|---|---|---|---|---|---|
| AZD1480 | Influence on STAT3 downstream target genes in presence of IL-6 | Western Blot | 0.25 µM | U266 | Homo sapiens | |||
| AZD1480 | Influence on STAT3 downstream target genes in presence of IL-6 | Western Blot | 0.50 µM | U266 | Homo sapiens | |||
| AZD1480 | Influence on STAT3 downstream target genes in presence of IL-6 | Western Blot | 1.00 µM | U266 | Homo sapiens | |||
| AZD1480 | Inhibition of in vitro xenograft growth | Western Blot | 30.00 mg/kg | Xenograft X1046 | Mus musculus | athymic nude mice |