| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
0.50 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
1.00 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
2.50 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
5.00 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
0.50 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
1.00 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
2.50 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
5.00 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
0.50 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
1.00 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
2.50 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
5.00 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Real Time PCR |
0.50 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Real Time PCR |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Real Time PCR |
0.50 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Real Time PCR |
0.50 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TPC-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
MZ-CRC1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
TT |
Homo sapiens |
|
|
|
| AZD1480 |
Inhibition of in vitro xenograft growth |
Western Blot |
30.00 mg/kg |
Xenograft X1046 |
Mus musculus |
athymic nude mice |
|
|
