| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.10 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
MEF-Stat3-YFP |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.10 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
1.00 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
DU145 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDA-MB-468 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
