| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Immunostaining |
30.00 mg/kg |
TPC-1 (xenograft) |
Mus musclus |
nu/nu Nude mice |
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
786-O |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
1.00 µM |
786-O |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
Renca |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
1.00 µM |
Renca |
Mus musclus |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
786-O |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
786-O |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
786-O |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
786-O |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Renca |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Renca |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Renca |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
Renca |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on cell motility |
Tube formation assay |
0.10 µM |
EC |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on cell motility |
Tube formation assay |
0.50 µM |
EC |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on cell motility |
Tube formation assay |
1.00 µM |
EC |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on tumor metastasis |
Number of nodules |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
STAT3 |
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
