| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
300.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
10.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
30.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
100.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
300.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
1000.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
PC-3 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
0.50 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
1.00 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
1.50 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Fluorometric immunosorbent enzyme assay |
800.00 nM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Fluorometric immunosorbent enzyme assay |
800.00 nM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
RD |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh41 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Rh30 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
BT-12 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
TC-71 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-9 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-258 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
SJ-GBM2 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
HB-1643 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
NB-EBc1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-90 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CHLA-136 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
NALM-6 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
COG-LL-317 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
RS4;11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
MOLt-4 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CCRF-CEM GM |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
CCRF-CEM-SY |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Kasumi-1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Karpas-299 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
DIMSCAN |
N/A nM |
Ramos-RA1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-6 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumour volume |
60.00 mg/kg |
KT-8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-13 |
Homo sapiens |
|
STAT3 |
|
