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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.25 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on STAT3 downstream target genes in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 2.00 µM Kms.11 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 0.50 µM HS-5 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 1.00 µM HS-5 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 2.00 µM HS-5 Homo sapiens
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.10 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.20 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.50 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 1.00 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 5.00 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 10.00 µM Homo sapiens p-STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.10 µM Homo sapiens STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.20 µM Homo sapiens STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 0.50 µM Homo sapiens STAT1
AZD1480 Influence on kinase activity Cell-free kinase assay; Western Blot 1.00 µM Homo sapiens STAT1