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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Cell Apoptosis Analysis Flow cytometry 0.50 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 0.80 µM U266 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 0.80 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 1.00 µM U266 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 1.00 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 1.50 µM U266 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 1.50 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 2.00 µM U266 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 2.00 µM RPMI 8226 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 2.00 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 3.00 µM RPMI 8226 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 0.50 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 0.50 µM U266 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 1.00 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 1.00 µM U266 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 2.00 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 2.00 µM U266 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 3.00 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition in presence of IL6 MTS Assay 3.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens STAT3