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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell motility Tube formation assay 0.10 µM HUVEC Homo sapiens BALB/c
AZD1480 Influence on cell motility Tube formation assay 0.50 µM HUVEC Homo sapiens BALB/c
AZD1480 Influence on cell motility Tube formation assay 1.00 µM HUVEC Homo sapiens BALB/c
AZD1480 Cell viability inhibition MTS Assay 0.50 µM U266 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 0.50 µM RPMI 8226 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 0.50 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 1.00 µM U266 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 1.00 µM RPMI 8226 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 1.00 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 2.00 µM U266 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 2.00 µM RPMI 8226 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 2.00 µM Kms.11 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 3.00 µM U266 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 3.00 µM RPMI 8226 Homo sapiens
AZD1480 Cell viability inhibition MTS Assay 3.00 µM Kms.11 Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry 0.50 µM U266 Homo sapiens