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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM OCL-LY7 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 2.00 µM OCL-LY7 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 5.00 µM OCL-LY7 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.30 µM NCI-H1650 Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM NCI-H1650 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM HCC 827 Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM HCC 827 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM AGS Homo sapiens p-STAT3
AZD1480 Influence on protein activity Western Blot 0.30 µM AGS Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM Hep3B Homo sapiens p-STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM Hep3B Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.05 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.25 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.05 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.25 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on protein-DNA interaction EMSA 0.10 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on protein-DNA interaction EMSA 0.50 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on protein-DNA interaction EMSA 1.00 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on cell viability MTS Assay 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens