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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM MO4 Mus musculus p-STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM MO4 Mus musculus p-STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM MO4 Mus musculus p-STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM MO4 Mus musculus
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM MO4 Mus musculus
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM MO4 Mus musculus
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM HD-LM2 Homo sapiens STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM HD-LM2 Homo sapiens STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM HD-LM2 Homo sapiens STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM HD-LM2 Homo sapiens STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 5.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Influence on protein activity Western Blot 0.10 µM L-428 Homo sapiens STAT1
AZD1480 Influence on protein activity Western Blot 0.50 µM L-428 Homo sapiens STAT1