AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
4.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
|
|
AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
4.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
AZD1480 |
Influence on protein activity |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT4 |
|
AZD1480 |
Influence on protein activity |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT3 |
|
AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT1 |
|
AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Western Blot |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
STAT3 |
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
STAT3 |
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-10 |
Homo sapiens |
|
|
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-13 |
Homo sapiens |
|
STAT3 |
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
20.00 mg/kg |
KT-13 |
Homo sapiens |
|
|
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-13 |
Homo sapiens |
|
STAT3 |
|
AZD1480 |
Influence on protein level in tumor tissue |
Western Blot |
10.00 mg/kg |
KT-13 |
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.10 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.20 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
10.00 µM |
|
Homo sapiens |
|
p-STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.10 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.20 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
10.00 µM |
|
Homo sapiens |
|
STAT1 |
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.20 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
10.00 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.20 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
|
|
AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
10.00 µM |
|
Homo sapiens |
|
|
|