| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PALLSD (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity in presence of selumetinib |
Western Blot |
1.00 µM |
PAMDRM (xenograft) |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
10.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
20.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
30.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
60.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
100.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
200.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
400.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5B |
|
