| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.25 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Kms.11 (xenograft) |
Mus musculus |
NOD/SCID IL2Rγ-null mice |
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
10.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
10.00 µM |
U251-MG |
Homo sapiens |
|
|
|
