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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Influence on protein activity Western Blot 0.50 µM 786-O Mus musclus p-STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM 786-O Mus musclus p-STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM 786-O Mus musclus STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM 786-O Mus musclus STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM Renca Mus musclus p-STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM Renca Mus musclus p-STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM Renca Mus musclus STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM Renca Mus musclus STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c p-STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c p-STAT3
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c STAT3
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM Kms.11 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 2.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Western Blot 1.00 µM Kms.11 Homo sapiens