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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DU145 Homo sapiens
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg DU145 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg DU145 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TT Homo sapiens