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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.05 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.25 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MDAH2774 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.25 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM DU145 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.25 µM DU145 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM DU145 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM DU145 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.10 µM DU145 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.25 µM DU145 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM DU145 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM DU145 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 3.00 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.30 µM MDAH2774 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM MDA-MB-468 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM DU145 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM DU145 Homo sapiens