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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg MEF-Stat3-YFP Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg DU145 (xenograft) Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 1.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 10.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 30.00 mg/kg TPC-1 (xenograft) Mus musclus
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Inhibition of in vitro xenograft growth Tumor volume 30.00 mg/kg Xenograft X1046 Mus musculus athymic nude mice
AZD1480 Inhibition of in vitro xenograft growth Tumor volume 30.00 mg/kg Xenograft X1066 Mus musculus athymic nude mice