AZD1480 |
Inhibition of in vitro xenograft growth |
Quantitative RT-PCR |
30.00 mg/kg |
Xenograft X1046 |
Mus musculus |
athymic nude mice |
|
|
AZD1480 |
|
Quantitative RT-PCR |
0.25 µM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
AZD1480 |
Influence on protein activity |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|
AZD1480 |
Influence on PLP-induced Relapsing-Remitting EAE Disease |
Quantitative RT-PCR |
25.00 mg/kg |
spinal cord |
Mus musculus |
c57BL/6 |
|
|