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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM U266 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.25 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 0.50 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in presence of IL6 Immunoprecipitation 1.00 µM Kms.11 Homo sapiens
AZD1480 Influence on protein activity in tumor tissue Immunoprecipitation 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Influence on protein activity in tumor tissue Immunoprecipitation 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Influence on protein activity in tumor tissue Immunoprecipitation 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Influence on protein activity in tumor tissue Immunoprecipitation 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Influence on protein activity Immunoprecipitation 5.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 10.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 20.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Rv1 Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 10.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 20.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 400.00 nM CWR22Rv1 Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 15.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 300.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 400.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 15.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Pc Homo sapiens STAT5B