| AZD1480 |
Influence on gene expression |
Real Time PCR |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Flow cytometry |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
5.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
5.00 µM |
MDCK |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
p-STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
5.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Immunoprecipitation |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Rv1 |
Homo sapiens |
|
STAT5B |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 nM |
CWR22Pc |
Homo sapiens |
|
STAT5B |
|
