| AZD1480 |
Influence on cell proliferation |
Trypan blue exclusion assay |
3.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-TYK2 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK3 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
p-STAT5 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
3.00 µM |
Ba/F3 TEL-JAK1 |
Mus musculus |
|
STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
3.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
3.00 µM |
RPMI 8226 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
3.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
3.00 µM |
RPMI 8226 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
3.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
3.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5A |
|
| AZD1480 |
Influence on transcriptional activity of protein |
Luciferase Reporter Gene Assay |
3.00 nM |
PC-3 |
Homo sapiens |
|
STAT5B |
|
