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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM ARPE19 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM HEK293 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM KCNR Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 2.50 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 2.50 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM TC32 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM KCNR Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM SY5Y Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM TC32 Homo sapiens