| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
ARPE19 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
KCNR |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
Rh18 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
TC32 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
Trypan blue exclusion assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 1 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 2 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
patient 3 |
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
2.00 µM |
OCL-LY7 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometr- annexin V staining |
2.00 µM |
MDCK |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Influence on cell cycle |
Ki67/DAPI cell proliferation assay |
2.00 µM |
CLBL-1 |
Canis lupus familiaris |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
2.00 µM |
RPMI 8226 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
2.00 µM |
RPMI 8226 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Viability |
DIMSCAN analysis |
2.00 µM |
PBMC |
Mus musculus |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
U266 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
2.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
2.00 µM |
HS-5 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
