| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on downstream gene transcription |
RT-qPCR |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Inhibition of protein signalling in human glioblastoma xenograft tumors |
RT-qPCR |
1.00 µM |
Xenograft X1016 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Inhibition of protein signalling in human glioblastoma xenograft tumors |
RT-qPCR |
1.00 µM |
Xenograft X1016 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Inhibition of protein signalling in human glioblastoma xenograft tumors |
RT-qPCR |
1.00 µM |
Xenograft X1016 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on CD133 expression in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on CD133 expression in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on CD133 expression in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on CD133 expression in tumor tissue in presence of OSM |
Western Blot |
1.00 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
p-STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKRSL (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALNTB (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKYEP (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PALJDL (xenograft) |
|
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
PAKHZT (xenograft) |
|
|
STAT3 |
|
