| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
1.00 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
1.00 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
1.00 µM |
HS-5 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
p-STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
1.00 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on cell proliferation |
WST-1 Cell Proliferation Assay |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
WST-1 Cell Proliferation Assay |
1.00 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
WST-1 Cell Proliferation Assay |
1.00 µM |
Murine Primary Astrocytes |
Mus musculus |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry- annexin V staining |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell motility |
Soft Agar Growth Assay |
1.00 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U251-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
U87-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
1.00 µM |
4C8 |
Homo sapiens |
|
STAT3 |
|
