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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) STAT1
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) p-STAT3
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) STAT3
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) p-STAT5
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft) STAT5
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PALLSD (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) p-STAT1
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) STAT1
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) p-STAT3
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) STAT3
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) p-STAT5
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft) STAT5
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft)
AZD1480 Influence on protein activity in presence of selumetinib Western Blot 1.00 µM PAMDRM (xenograft)
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM CWR22Rv1 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM PC-3 Homo sapiens
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM DU145 Homo sapiens
AZD1480 Influence on cell apoptosis FACS 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM BMDM Mus musculus c57BL/6 STAT1
AZD1480 Influence on protein activity Western Blot 1.00 µM BMDM Mus musculus c57BL/6 STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM BMDM Mus musculus c57BL/6 STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM BMDM Mus musculus c57BL/6
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM BMDM Mus musculus c57BL/6
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM BMDM Mus musculus c57BL/6 STAT1