| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
HS-5 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
p-STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
STAT1 |
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on kinase activity |
Cell-free kinase assay; Western Blot |
0.50 µM |
|
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
|
|
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U87-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
4C8 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of OSM |
Western Blot |
0.50 µM |
U251-MG |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue in presence of OSM |
Western Blot |
0.50 µM |
Xenograft X1066 |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on cell apoptosis |
FACS |
0.50 µM |
CWR22Pc |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT5 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
BMDM |
Mus musculus |
c57BL/6 |
STAT1 |
|
| AZD1480 |
Influence on MHC expression |
Flow cytometry |
0.50 µM |
DCs |
Mus musculus |
c57BL/6 |
|
|
