| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Flow cytometry- annexin V staining |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Western Blot |
0.50 µM |
LN-17 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
DU145 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
786-O |
Mus musclus |
|
|
|
| AZD1480 |
Influence on cell viability |
MTS Assay |
0.50 µM |
Renca |
Mus musclus |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
786-O |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
786-O |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Renca |
Mus musclus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
Renca |
Mus musclus |
|
STAT3 |
|
| AZD1480 |
Influence on cell motility |
Tube formation assay |
0.50 µM |
EC |
Mus musclus |
BALB/c |
|
|
| AZD1480 |
Influence on cell motility |
Tube formation assay |
0.50 µM |
HUVEC |
Homo sapiens |
BALB/c |
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
0.50 µM |
RPMI 8226 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition |
MTS Assay |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell Apoptosis Analysis |
Flow cytometry |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Cell viability inhibition in presence of IL6 |
MTS Assay |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Immunoprecipitation |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL6 |
Western Blot |
0.50 µM |
Kms.11 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream target genes in presence of IL-6 |
Western Blot |
0.50 µM |
U266 |
Homo sapiens |
|
|
|
