AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
p-STAT3 |
|
AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
STAT3 |
|
AS1810722 |
Influence on protein activity in presence of FBS |
Western Blot |
0.10 µM |
HUVECS |
Homo sapiens (patient) |
|
|
|
AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.10 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|