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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AS1810722 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM fibroblast-like synoviocytes (FLS) Homo sapiens (patient) p-STAT3
AS1810722 Influence on protein activity in presence of IL-6 Western Blot 0.10 µM fibroblast-like synoviocytes (FLS) Homo sapiens (patient) STAT3
AS1810722 Influence on protein activity in presence of FBS Western Blot 0.10 µM HUVECS Homo sapiens (patient)
AS1810722 Influence on cell differentiation ELISA 0.10 nM Th1 Mus musculus c57BL/6
AS1810722 Influence on cell differentiation ELISA 0.10 nM Th2 Mus musculus c57BL/6
AS1810722 Influence on eosinophils accumulation in BALF Differential cell count 0.10 mg/kg eosinophil Mus musculus BALB/c