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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus p-STAT6
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus STAT6
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in serum ELISA 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in serum ELISA 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in serum ELISA 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway STAT6
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity in transplanted tissue Western Blot 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 p-STAT6 (Y641)
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 STAT6
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 7 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 p-STAT6 (Y641)
AS1517499 Influence on protein activity 7 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 STAT6
AS1517499 Influence on protein activity 7 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 14 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 p-STAT6 (Y641)
AS1517499 Influence on protein activity 14 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6 STAT6
AS1517499 Influence on protein activity 14 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 7 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 14 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 14 days post-bleomycin treatment Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on protein activity 7 days post-bleomycin treatment Immuinofluorescence 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on protein activity 2 days post-bleomycin treatment Immuinofluorescence 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on STAT6 dependent genes RT-qPCR 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on STAT6 dependent genes RT-qPCR 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on STAT6 dependent proteins Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on STAT6 dependent proteins Western Blot 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on STAT6 dependent genes Immunofluorescence 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on gene expression 2 days post-bleomycin treatment RT-qPCR 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on gene expression 2 days post-bleomycin treatment RT-qPCR 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on gene expression 7 days post-bleomycin treatment RT-qPCR 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on gene expression 7 days post-bleomycin treatment RT-qPCR 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on gene expression 14 days post-bleomycin treatment RT-qPCR 10.00 mg/kg lung tissue Mus musculus c57BL/6
AS1517499 Influence on gene expression 14 days post-bleomycin treatment RT-qPCR 10.00 mg/kg alveolar macrophages Mus musculus c57BL/6
AS1517499 Influence on gene expression 2 days post-bleomycin treatment RT-qPCR 10.00 mg/kg lung tissue Mus musculus c57BL/6