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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens p-STAT3
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens STAT3
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IL-6 Luciferase promoter assay 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 1.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 5.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 100.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 1.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 5.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 100.00 µM RT4 Homo sapiens
AG490 Influence on gene expression levels RT-PCR 50.00 µM RT4 Homo sapiens
AG490 Influence on gene expression levels RT-PCR 50.00 µM RT4 Homo sapiens
AG490 Influence on protein degradation Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of protease inhibitors Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of protease inhibitors Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein synthesis Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein synthesis Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens p-STAT3
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens STAT3
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM 1774 macrophages Homo sapiens STAT1α
AG490 Influence on protein activity in presence of IFNγ Western Blot 100.00 µM 1774 macrophages Homo sapiens STAT1α
AG490 Influence on nitric oxide (NO) generation Griess reaction 3.00 µM 1774 macrophages Homo sapiens
AG490 Influence on nitric oxide (NO) generation Griess reaction 10.00 µM 1774 macrophages Homo sapiens
AG490 Influence on nitric oxide (NO) generation Griess reaction 30.00 µM 1774 macrophages Homo sapiens
AG490 Influence on protein activity in presence of IFNγ Western Blot 3.00 µM 1774 macrophages Homo sapiens
AG490 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM 1774 macrophages Homo sapiens
AG490 Influence on gene expression levels in presence of IFNγ RT-qPCR 10.00 µM 1774 macrophages Homo sapiens
AG490 Influence on gene expression levels in presence of IFNγ RT-qPCR 10.00 µM 1774 macrophages Homo sapiens
AG490 Influence on cell viability MMT 20.00 µM SW1990 Homo sapiens
AG490 Influence on gene expression levels RT-qPCR 20.00 µM SW1990 Homo sapiens
AG490 Influence on gene expression levels RT-qPCR 20.00 µM SW1990 Homo sapiens
AG490 Influence on protein activity Immunocytochemistry 20.00 µM SW1990 Homo sapiens STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens p-STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens