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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens p-STAT3
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens STAT3
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 1.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 5.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 100.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 1.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 5.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 100.00 µM RT4 Homo sapiens
AG490 Influence on protein degradation Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of protease inhibitors Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of protease inhibitors Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein synthesis Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein synthesis Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influene on protein activity in presence of ER stress inducer Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens p-STAT3
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens STAT3
AG490 Influence on correlation between proetin levels and IL-6 response Western Blot 50.00 µM RT4 Homo sapiens
AG490 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM 1774 macrophages Homo sapiens STAT1α
AG490 Influence on protein activity in presence of IFNγ Western Blot 100.00 µM 1774 macrophages Homo sapiens STAT1α
AG490 Influence on protein activity in presence of IFNγ Western Blot 3.00 µM 1774 macrophages Homo sapiens
AG490 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM 1774 macrophages Homo sapiens
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats p-STAT1
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats STAT1
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats p-STAT3
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats STAT3
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats p-STAT5
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats STAT5
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens p-STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens STAT3