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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens p-STAT3
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM J82 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 80.00 µM J82 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM RT112 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 80.00 µM RT112 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM A2780 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM A2780 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM A2780 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM OVCAR-429 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM OVCAR-429 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM OVCAR-429 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM OVCAR-433 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM OVCAR-433 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM OVCAR-433 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 25.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 50.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 75.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM J82 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 80.00 µM J82 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM RT112 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 80.00 µM RT112 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM SKOV-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM OVCAR-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM OVCAR-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM OVCAR-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 25.00 µM TOV-21G Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 50.00 µM TOV-21G Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (S727)